Well, I got TTW 2.2a running, and so far I gotta say it's been really smooth and I am really enjoying it. It's really stable and despite running as New Vegas, actually runs a bit smoother than NV does on my computer typically. That might just be for the Capital Wasteland though, haven't been to the Mojave yet. We'll see.
Nonetheless, it's great. I have come across a few glitches or things out of place, but most of them seem to either be A. known with a fix, or B. Known with progress being made to fix them. An example is the Rivet City NPC glitch outside of the market. Here are a couple of the things I have noticed that I did not see reported yet. These are minor but I thought I'd mention them nonetheless.
1. At the birthday Party in 101, when Andy cuts the cake the cake just vanishes.
2. At the birthday party once again, when the overseer leaves, instead of going upstairs he walked down to the reactor room. Almost like he had the same script to walk there as James or something. I played through the birthday scene twice and both of these incidents occurred both times.
3. When somebody speaks over an intercom, there is no distortion in the audio. Normally in the game a voice over the intercom has a slight static-y distortion to it and sounds a tad more quiet than regular dialogue, but they sound like they're face-to-face to me here. This has happened at: Vault 101 when Jonas speaks over the intercom at the party (The party seems full of surprises with me, I know. XD), at Tenpenny Tower with Chief Gustavo when he lets you in, and at Rivet City with Harkness before extending the bridge.