There is a mod like this made by "CourierSix" but unfortunately he hasnt been online for over 8 months (as i am writing this) and have not updated it for the newest TTW version. So i figured i might as well do it. What this mod aims to do is to make ALL UNNAMED npcs (and most creatures aswell) karma set to neutral. This way you wont become a saint just for shooting a few ghouls, this also applies the other way. It does NOT change any named npcs karma so you.
Note; that one thing i changed from CourierSix's version is that i set SOME unnamed GOOD npcs to neutral mostly wastelander tho.
NPCS/Factions that this mod changes.
Pitt Raiders and Slaves (this way you wont lose karma if you side with the raiders)
SOME Legionnaires (most of them were already neutral suprisingly)
ALMOST ALL CREATURES
And much more that i have forgotten about.
LEGAL NOTICE; before anybody yells at me for stealing "CourierSix"s work please note that i have done EVERYTHING from scratch. The only thing we have in common is the idea for the mod.